Recombinant humaan NKG2C/KLRC2-eiwit

NKG2-C type II integral membrane protein, also known as KLRC2, plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. The group, designated KLRC (NKG2) are expressed primarily in natural killer (NK) cells and encodes a family of transmembrane proteins characterized by a type II membrane orientation (extracellular C terminus) and the presence of a C-type lectin domain. The KLRC (NKG2) gene family is located within the NK complex, a region that contains several C-type lectin genes preferentially expressed on NK cells. KLRC2 alternative splice variants have been described but their full-length nature has not been determined. Recombinant human KLRC2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

18.4 kDa (162aa)

KLRC2, NKG2-C type II integral membrane protein, CD159c, NKG2-C, NKG2C, ATGP1679-10 µg, ATGP1679-20 µg, ATGP1679-50 µg, ATGP1679-100 µg, ATGP1679-250 µg, ATGP1679-500 µg, ATGP1679-1 mg, ATGP1679-10, ATGP1679-20, ATGP1679-50, ATGP1679-100, ATGP1679-250, ATGP1679-500, ATGP1679-1

Houchins J.P., et al. (1991) J. Exp. Med. 173:1017-1020; ; Shum B.P., et al. (2002) J. Immunol. 168:240-252

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Immunology

NP_002251

P26717

Human

MGSSHHHHHH SSGLVPRGSH MGSMIPFLEQ NNFSPNTRTQ KARHCGHCPE EWITYSNSCY YIGKERRTWE ESLLACTSKN SSLLSIDNEE EMKFLASILP SSWIGVFRNS SHHPWVTING LAFKHKIKDS DNAELNCAVL QVNRLKSAQC GSSMIYHCKH KL