Recombinant humaan NKp30/NCR3-eiwit

NCR3, also known as NKP30, is a natural cytotoxicity receptor (NCR) that may aid NK cells in the lysis of tumor cells. The encoded protein interacts with CD3-zeta (CD247), a T-cell receptor. A single nucleotide polymorphism in the 5' untranslated region of this gene has been associated with mild malaria suceptibility. Three transcript variants encoding different isoforms have been found for this gene. Recombinant human NCR3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Natural cytotoxicity triggering receptor 3, 1C7, CD337, LY117, MALS, NKp30

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

15.3 kDa (141aa) confirmed by MALDI-TOF

NKp30, NCR3, Natural cytotoxicity triggering receptor 3, 1C7, CD337, LY117, MALS, NKp30, ATGP2583-10 µg, ATGP2583-20 µg, ATGP2583-50 µg, ATGP2583-100 µg, ATGP2583-250 µg, ATGP2583-500 µg, ATGP2583-1 mg, ATGP2583-10, ATGP2583-20, ATGP2583-50, ATGP2583-100, ATGP2583-250, ATGP2583-500, ATGP2583-1

Venter J.C., et al. (2001) Science. 291:1304-1351; ; Gerhard D.S., et al. (2004) Genome Res. 14:2121-2127;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT

Stem Cell

NP_001138939

O14931

Human

MGSSHHHHHH SSGLVPRGSH MLWVSQPPEI RTLEGSSAFL PCSFNASQGR LAIGSVTWFR DEVVPGKEVR NGTPEFRGRL APLASSRFLH DHQAELHIRD VRGHDASIYV CRVEVLGLGV GTGNGTRLVV EKEHPQLGAG T