Recombinant humaan NKp44/NCR2-eiwit

NCR2 belongs to the natural cytotoxicity receptor (NCR) family and contains 1 Ig-like (immunoglobulin-like) domain. This protein interacts with TYROBP/DAP12 and is selectively expressed by activated NK cells and by in vitro cultured (i. e. activated) TCRg/d lymphoid cells. NCR2 is a cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Recombinant human NKP44 protein, fused to His-tag at N-terminus, was expressed in E. coli

Natural cytotoxicity triggering receptor 2 isoform 1, CD336, LY95, NK-p44 NKP44

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

15 kDa (133aa)

NKp44, NCR2, Natural cytotoxicity triggering receptor 2 isoform 1, CD336, LY95, NK-p44 NKP44, ATGP2499-10 µg, ATGP2499-20 µg, ATGP2499-50 µg, ATGP2499-100 µg, ATGP2499-250 µg, ATGP2499-500 µg, ATGP2499-1 mg, ATGP2499-10, ATGP2499-20, ATGP2499-50, ATGP2499-100, ATGP2499-250, ATGP2499-500, ATGP2499-1

Vitale M, Bottino C et al. (1998) J Exp Med. 15; ;187 (12) :2065-72.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Signal Transduction

NP_004819.2

O95944

Human

MGSSHHHHHH SSGLVPRGSH MSQAQSKAQV LQSVAGQTLT VRCQYPPTGS LYEKKGWCKE ASALVCIRLV TSSKPRTMAW TSRFTIWDDP DAGFFTVTMT DLREEDSGHY WCRIYRPSDN SVSKSVRFYL VVS