Recombinant humaan NKX3.1 eiwit

NKX3-1 is a homeobox-containing transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of NKX3-1 is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this. Recombinant human NKX3-1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Homeobox protein Nkx-3.1, BAPX2, NKX3, NKX3.1, NKX3A, NKX3-1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

28.7 kDa (257aa)

NKX3.1, Homeobox protein Nkx-3.1, BAPX2, NKX3, NKX3.1, NKX3A, ATGP1882-10 µg, ATGP1882-20 µg, ATGP1882-50 µg, ATGP1882-100 µg, ATGP1882-250 µg, ATGP1882-500 µg, ATGP1882-1 mg, ATGP1882-10, ATGP1882-20, ATGP1882-50, ATGP1882-100, ATGP1882-250, ATGP1882-500, ATGP1882-1

Anderson, P.D., et al. (2012) . Clin. Invest. 122 (5), 1907-1919; ; Tan, P.Y., et al. (2012) Mol. Cell. Biol. 32 (2), 399-414;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M UREA, 10% glycerol

Epigenomics (Transcription & Translation)

NP_006158

Q99801

Human

MLRVPEP RPGEAKAEGA APPTPSKPLT SFLIQDILRD GAQRQGGRTS SQRQRDPEPE PEPEPEGGRS RAGAQNDQLS TGPRAAPEEA ETLAETEPER HLGSYLLDSE NTSGALPRLP QTPKQPQKRS RAAFSHTQVI ELERKFSHQK YLSAPERAHL AKNLKLTETQ VKIWFQNRRY KTKRKQLSSE LGDLEKHSSL PALKEEAFSR ASLVSVYNSY PYYPYLYCVG SWSPAFW