Recombinant humaan NRIGE-eiwit

MAGED1, as known as Melanoma-associated antigen D1, is expressed in almost all normal adult tissues. It has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. It has been involved in Prader-Willi syndrome, which includes hyperphagia, repetitive and compulsive behaviors, and cognitive impairment. Recombinant human MAGED1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Melanoma-associated antigen D1 isoform a, DLXIN-1, NRAGE

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

31.7 kDa (280aa) confirmed by MALDI-TOF

NRAGE, Melanoma-associated antigen D1 isoform a, DLXIN-1, NRAGE, ATGP2455-10 µg, ATGP2455-20 µg, ATGP2455-50 µg, ATGP2455-100 µg, ATGP2455-250 µg, ATGP2455-500 µg, ATGP2455-1 mg, ATGP2455-10, ATGP2455-20, ATGP2455-50, ATGP2455-100, ATGP2455-250, ATGP2455-500, ATGP2455-1

Dombret C. et al. (2012) Hum Mol Genet. 21:4703-4717; ; Mouri , . et al. (2012) J Neurosci. 32:4562-4580.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT

Apoptosis

NP_001005333

Q9Y5V3

Human

MGSSHHHHHH SSGLVPRGSH MGSLRPSPNS RASQNPGAAQ PRDVALLQER ANKLVKYLML KDYTKVPIKR SEMLRDIIRE YTDVYPEIIE RACFVLEKKF GIQLKEIDKE EHLYILISTP ESLAGILGTT KDTPKLGLLL VILGVIFMNG NRASEAVLWE ALRKMGLRPG VRHPLLGDLR KLLTYEFVKQ KYLDYRRVPN SNPPEYEFLW GLRSYHETSK MKVLRFIAEV QKRDPRDWTA QFMEAADEAL DALDAAAAEA EARAEARTRM GIGDEAVSGP