Recombinant humaan NUDT9-eiwit

NuDT9 belongs to a superfamily of Nudix hydrolases. It is known to function as a highly specific adenosine diphosphate ribose pyrophosphatase that hydrolyzes ADP ribose to AMP and ribose 5'-phosphate. It has been suggested that NuDT9 may be involved in the regulation of the menstrual cycle and may be related to the proliferation of glandular cells in the human endometrium. Recombinant human NuDT9 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Nudix hydrolase 9, ADP-ribose pyrophosphatase mitochondrial, ADP-ribose diphosphatase, Adenosine diphosphoribose pyrophosphatase, ADPR-Ppase, Nucleoside diphosphate-linked moiety X motif 9, Nudix motif 9, NUDT10

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

36.5 kDa (325aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

NUDT9, ADP-ribose pyrophosphatase mitochondrial isoform a., ADP-ribose pyrophosphatase, mitochondrial isoform a., MGC3037, NuDT10, ATGP1062-10 µg, ATGP1062-20 µg, ATGP1062-50 µg, ATGP1062-100 µg, ATGP1062-250 µg, ATGP1062-500 µg, ATGP1062-1 mg, ATGP1062-10, ATGP1062-20, ATGP1062-50, ATGP1062-100, ATGP1062-250, ATGP1062-500, ATGP1062-1

Perraud AL., et al. (2001) Nature. 411 (6837) :595-9. ; ; Perraud AL., et al. (2003) J Biol Chem. 278 (3) :1794-801.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1M NaCl.

Signal Transduction

NP_076952

Q9BW91

Human

NTNVMSGSN GSKENSHNKA RTSPYPGSKV ERSQVPNEKV GWLVEWQDYK PVEYTAVSVL AGPRWADPQI SESNFSPKFN EKDGHVERKS KNGLYEIENG RPRNPAGRTG LVGRGLLGRW GPNHAADPII TRWKRDSSGN KIMHPVSGKH ILQFVAIKRK DCGEWAIPGG MVDPGEKISA TLKREFGEEA LNSLQKTSAE KREIEEKLHK LFSQDHLVIY KGYVDDPRNT DNAWMETEAV NYHDETGEIM DNLMLEAGDD AGKVKWVDIN DKLKLYASHS QFIKLVAEKR DAHWSEDSEA DCHAL