Recombinant humaan OXSR1-eiwit

OXSR1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. This protein regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. It is associated with secretory granules and modulates synaptic transmission and synaptic plasticity. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human OXSR1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Serine/threonine-protein kinase OSR1, KIAA1101, OSR1, Oxidative stress-responsive 1 protein, Serine threonine-protein kinase OSR1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

60.4. kDa (550aa)

OXSR1, Serine/threonine-protein kinase OSR1, KIAA1101, OSR1, Oxidative stress-responsive 1 protein, Serine threonine-protein kinase OSR1, ATGP2848-10 µg, ATGP2848-20 µg, ATGP2848-50 µg, ATGP2848-100 µg, ATGP2848-250 µg, ATGP2848-500 µg, ATGP2848-1 mg, ATGP2848-10, ATGP2848-20, ATGP2848-50, ATGP2848-100, ATGP2848-250, ATGP2848-500, ATGP2848-1

Nakamura T.Y., et al, (2001) Proc. Natl. Acad. Sci. u.S.A. 98:12808-12813.; ; Bahi N., et al, (2003) Hum. Mol. Genet. 12:1415-1425.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 30% glycerol, 1mM DTT

Signal Transduction

NP_005100

O95747

Human

MGSSHHHHHH SSGLVPRGSH MGSMSEDSSA LPWSINRDDY ELQEVIGSGA TAVVQAAYCA PKKEKVAIKR INLEKCQTSM DELLKEIQAM SQCHHPNIVS YYTSFVVKDE LWLVMKLLSG GSVLDIIKHI VAKGEHKSGV LDESTIATIL REVLEGLEYL HKNGQIHRDV KAGNILLGED GSVQIADFGV SAFLATGGDI TRNKVRKTFV GTPCWMAPEV MEQVRGYDFK ADIWSFGITA IELATGAAPY HKYPPMKVLM LTLQNDPPSL ETGVQDKEML KKYGKSFRKM ISLCLQKDPE KRPTAAELLR HKFFQKAKNK EFLQEKTLQR APTISERAKK VRRVPGSSGR LHKTEDGGWE WSDDEFDEES EEGKAAISQL RSPRVKESIS NSELFPTTDP VGTLLQVPEQ ISAHLPQPAG QIATQPTQVS LPPTAEPAKT AQALSSGSGS QETKIPISLV LRLRNSKKEL NDIRFEFTPG RDTAEGVSQE LISAGLVDGR DLVIVAANLQ KIVEEPQSNR SVTFKLASGV EGSDIPDDGK LIGFAQLSIS