Recombinant humaan p130 Cas-eiwit

BCAR1, or CAS, is an Src family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion. Recombinant human BCAR1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Breast cancer anti-estrogen resistance 1, CAS, CAS1, CASS1, CRKAS, P130Cas

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

43.9 kDa (407aa)

P130Cas, breast cancer anti-estrogen resistance 1, CAS, CAS1, CASS1, CRKAS, P130Cas, ATGP2538-10 µg, ATGP2538-20 µg, ATGP2538-50 µg, ATGP2538-100 µg, ATGP2538-250 µg, ATGP2538-500 µg, ATGP2538-1 mg, ATGP2538-10, ATGP2538-20, ATGP2538-50, ATGP2538-100, ATGP2538-250, ATGP2538-500, ATGP2538-1

Konstantinovsky, S, et al. (2012) Clin. Exp. Metastasis 29 (6), 527-540; ; Huang, W., et al. (2012) PLoS ONE 7 (4), E36124;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol

Cancer

NP_055382

P56945

Human

MGSSHHHHHH SSGLVPRGSH MGSRLQQGVS ATVAHLLDLA GSAGATGSWR SPSEPQEPLV QDLQAAVAAV QSAVHELLEF ARSAVGNAAH TSDRALHAKL SRQLQKMEDV HQTLVAHGQA LDAGRGGSGA TLEDLDRLVA CSRAVPEDAK QLASFLHGNA SLLFRRTKAT APGPEGGGTL HPNPTDKTSS IQSRPLPSPP KFTSQDSPDG QYENSEGGWM EDYDYVHLQG KEEFEKTQKE LLEKGSITRQ GKSQLELQQL KQFERLEQEV SRPIDHDLAN WTPAQPLAPG RTGGLGPSDR QLLLFYLEQC EANLTTLTNA VDAFFTAVAT NQPPKIFVAH SKFVILSAHK LVFIGDTLSR QAKAADVRSQ VTHYSNLLCD LLRGIVATTK AAALQYPSPS AAQDMVE