Recombinant humaan p23/PTGES3-eiwit

Prostaglandin E synthase 3 (PTGES3), also known as P23 or TEBP (Telomerase binding protein p23), is a ubiquitously expressed protein that functions as a cochaperone and plays an important role in signal transduction. This protein is a molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Recombinant PTGES3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

PTGES3, cPGES, P23, TEBP, HSP90 co-chaperone, Sid 3177, Co chaperone p23, Hsp90 co chaperone, Cytosolic prostaglandin E2 synthase, Progesterone receptor complex, Progesterone receptor complex p23, Prostaglandin E synthase 3, PTGES 3, Telomerase binding protein p23, unactive progesterone receptor 23 kD

E.coli

Human

Non-Tagged

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

18.6 kDa (160aa) confirmed by MALDI-TOF

P23, PTGES3, PTGES3, cPGES, P23, TEBP, HSP90 co-chaperone, Sid 3177, Co chaperone p23, Hsp90 co chaperone, Cytosolic prostaglandin E2 synthase, Progesterone receptor complex, Progesterone receptor complex p23, Prostaglandin E synthase 3, PTGES 3, Telomerase binding protein p23, unactive progesterone receptor 23 kD, ATGP0418-10 µg, ATGP0418-20 µg, ATGP0418-50 µg, ATGP0418-100 µg, ATGP0418-250 µg, ATGP0418-500 µg, ATGP0418-1 mg, ATGP0418-10, ATGP0418-20, ATGP0418-50, ATGP0418-100, ATGP0418-250, ATGP0418-500, ATGP0418-1

Hawkins GA., et al. (2009) J Allergy Clin Immunol. 123 (6) :1376-83.e7; ; Nuttinck F., et al. (2008) Reproduction. 135 (5) :593-603.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Heat Shock Proteins

NP_006592

Q15185

Human

MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMNNM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE