Recombinant humaan p38-delta/MAPK13-eiwit

MAPK13, also known as mitogen-activated protein kinase 13, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. It is a related protein that is phosphorylated by MKK6 in response to cytokines and cellular stresses. Recombinant human MAPK13 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Mitogen-activated protein kinase 13, MGC99536, p38delta, PRKM13, SAPK4

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

44.2 kDa (385aa) confirmed by MALDI-TOF

MAPK13, Mitogen-activated protein kinase 13, MGC99536, p38delta, PRKM13, SAPK4, ATGP1285-10 µg, ATGP1285-20 µg, ATGP1285-50 µg, ATGP1285-100 µg, ATGP1285-250 µg, ATGP1285-500 µg, ATGP1285-1 mg, ATGP1285-10, ATGP1285-20, ATGP1285-50, ATGP1285-100, ATGP1285-250, ATGP1285-500, ATGP1285-1

Nishida E. et al. (1993) Trends Biochem. Sci. 18: 128-131.; ; Wang X.S. et al. (1997) J. Biol. Chem. 272: 23668-23674.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT

Cell Cycle

NP_002745.1

O15264

Human

MSLIRKKGFY KQDVNKTAWE LPKTYVSPTH VGSGAYGSVC SAIDKRSGEK VAIKKLSRPF QSEIFAKRAY RELLLLKHMQ HENVIGLLDV FTPASSLRNF YDFYLVMPFM QTDLQKIMGM EFSEEKIQYL VYQMLKGLKY IHSAGVVHRD LKPGNLAVNE DCELKILDFG LARHADAEMT GYVVTRWYRA PEVILSWMHY NQTVDIWSVG CIMAEMLTGK TLFKGKDYLD QLTQILKVTG VPGTEFVQKL NDKAAKSYIQ SLPQTPRKDF TQLFPRASPQ AADLLEKMLE LDVDKRLTAA QALTHPFFEP FRDPEEETEA QQPFDDSLEH EKLTVDEWKQ HIYKEIVNFS PIARKDSRRR SGMKL