Recombinant humaan Parvalbumin alfa/PVALB-eiwit

Parvalbumin alpha, also known PVALB, belongs to a larger group of EF hand proteins. It is a high affinity calcium ion-binding protein that is structurally and functionally similar to calmodulin and troponin C. Parvalbumin is expressed in a specific population of GABAergic interneurones which are thought to play a role in maintaining the balance between excitation and inhibition in the cortex as well as the hippocampus. Recombinant human PVALB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Parvalbumin alpha

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

14.6 kDa (134aa) confirmed by MALDI-TOF

Parvalbumin a, PVALB, Parvalbumin alpha, ATGP0779-10 µg, ATGP0779-20 µg, ATGP0779-50 µg, ATGP0779-100 µg, ATGP0779-250 µg, ATGP0779-500 µg, ATGP0779-1 mg, ATGP0779-10, ATGP0779-20, ATGP0779-50, ATGP0779-100, ATGP0779-250, ATGP0779-500, ATGP0779-1

Klausberqer T., et al. (2005) J Neurosci. 25 (42) :9782-93.; ; Conde F., et al. (1994) J Comp Neurol. 341 (1) :95-116.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 50 mM NaCl

Neuroscience

NP_002845

P20472

Human

MGSSHHHHHH SSGLVPRGSH MGSHMSMTDL LNAEDIKKAV GAFSATDSFD HKKFFQMVGLKKKSADDVKK VFHMLDKDKS GFIEEDELGF ILKGFSPDAR DLSAKETKML MAAGDKDGDG KIGVDEFSTL VAES