Recombinant humaan PDCD4-eiwit

PDCD4, also known as Programmed cell death 4, encodes a tumor suppressor protein whose expression is lost in progressed carcinomas of lung, breast, colon, and prostate. The expression of PDCD4 gene is strongly induced during apoptosis in a number of cell types. It is modulated by cytokines in natural killer and T cells. Recombinant human PDCD4, was expressed in E. coli and purified by conventional chromatography techniques.

Programmed cell death protein 4 isoform 1, H731

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

51.7 kDa (469aa)

PDCD4, Programmed cell death protein 4 isoform 1, H731, ATGP3833-10 µg, ATGP3833-20 µg, ATGP3833-50 µg, ATGP3833-100 µg, ATGP3833-250 µg, ATGP3833-500 µg, ATGP3833-1 mg, ATGP3833-10, ATGP3833-20, ATGP3833-50, ATGP3833-100, ATGP3833-250, ATGP3833-500, ATGP3833-1

Yoshinaga H., et al. (1999) Pathol lnt. 49 (12) :1067-77; ; Palamarchuk A., et al. (2005) Cancer Res. 65 (24) :11282-6.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 1mM DTT

Cancer

NP_055271

Q53EL6

Human

MDVENEQILN VNPADPDNLS DSLFSGDEEN AGTEEIKNEI NGNWISASSI NEARINAKAK RRLRKNSSRD SGRGDSVSDS GSDALRSGLT VPTSPKGRLL DRRSRSGKGR GLPKKGGAGG KGVWGTPGQV YDVEEVDVKD PNYDDDQENC VYETVVLPLD ERAFEKTLTP IIQEYFEHGD TNEVAEMLRD LNLGEMKSGV PVLAVSLALE GKASHREMTS KLLSDLCGTV MSTTDVEKSF DKLLKDLPEL ALDTPRAPQL VGQFIARAVG DGILCNTYID SYKGTVDCVQ ARAALDKATV LLSMSKGGKR KDSVWGSGGG QQSVNHLVKE IDMLLKEYLL SGDISEAEHC LKELEVPHFH HELVYEAIIM VLESTGESTF KMILDLLKSL WKSSTITVDQ MKRGYERIYN EIPDINLDVP HSYSVLERFV EECFQAGIIS KQLRDLCPSR GRKRFVSEGD GGRLKPESY