Recombinant humaan PDGF-B eiwit

PDGFB, also known as, Platelet-derived growth factor subunit B isoform 2, is a member of Platelet derived growth factor (PDGF) family. In general, PDGF isoforms are potent mitogens for connective tissue cells, including dermal fibroblasts, glial cells, arterial smooth muscle cells and some epithelial and endothelial cells. In addition to its activity as a mitogen. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. Recombinant human PDGFB, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Platelet-derived growth factor subunit B isoform 2, Platelet-derived growth factor subunit B isoform 2, c-sis, IBGC5, PDGF-2, PDGF2, SIS, SSV

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

14.7 kDa (130aa) confirmed by MALDI-TOF

PDGF-B, Platelet-derived growth factor subunit B isoform 2, Platelet-derived growth factor subunit B isoform 2, c-sis, IBGC5, PDGF-2, PDGF2, SIS, SSV, ATGP3007-10 µg, ATGP3007-20 µg, ATGP3007-50 µg, ATGP3007-100 µg, ATGP3007-250 µg, ATGP3007-500 µg, ATGP3007-1 mg, ATGP3007-10, ATGP3007-20, ATGP3007-50, ATGP3007-100, ATGP3007-250, ATGP3007-500, ATGP3007-1

Van Steensel L., et al. (2012) J Clin Endocrinol Metab. 97 (6) : 37062-37071.; ; Malabanan KP, et al. (2012) Am J Pathol. 180 (6) : 2590-7.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Cardiovascular

NP_148937.1

P01127

Human

CKTRTEVFE ISRRLIDRTN ANFLVWPPCV EVQRCSGCCN NRNVQCRPTQ VQLRPVQVRK IEIVRKKPIF KKATVTLEDH LACKCETVAA ARPVTRSPGG SQEQRAKTPQ