Recombinant humaan PDGF-BB eiwit

Molecular weight: 12.42 KDaDescription: Recombinant Human Platelet-Derived Growth Factor BB is produced by our E.coli and the target gene encoding Ser82-Thr190 is expressed.Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma.Binding of PDGFB to its receptor elicits a variety of cellular responses. In addition, PDGFB is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

PDGFBB; PDGF-BB

P01127

PDGF-BB

Lyophilized from a 0.2 ?m filtered solution of 20mM NaAc-HAc, pH 4.5.

Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing) . Lyophilized proteins are shipped at ambient temperature.