Recombinant humaan PDRG1-eiwit

PDRG1, also known as PDRG or C20orf126, is a 133 amino acid protein that localizes to the cytoplasm and belongs to the prefoldin subunit beta family. Expressed predominately in normal testicular tissue, PDRG1 is functionally induced by ultraviolet light and is thought to play a role in chaperone-mediated protein folding, possibly playing a role in cellular degradation. It is associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Recombinant human PDRG1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

P53 and DNA-damage regulated 1, C20orf126, PDRG

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

17.6 kDa (153aa) confirmed by MALDI-TOF

PDRG1, p53 and DNA-damage regulated 1, C20orf126, PDRG, ATGP0785-10 µg, ATGP0785-20 µg, ATGP0785-50 µg, ATGP0785-100 µg, ATGP0785-250 µg, ATGP0785-500 µg, ATGP0785-1 mg, ATGP0785-10, ATGP0785-20, ATGP0785-50, ATGP0785-100, ATGP0785-250, ATGP0785-500, ATGP0785-1

Russell RB., et al. (2008) Nat Chem Biol. 4 (11) :666-73.; ; Luo X., et al. (2003) Oncogene. 22 (46) :7247-57.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 5mM DTT, 20% glycerol

Heat Shock Proteins

NP_110442

Q9NUG6

Human

MLSPEAERVL RYLVEVEELA EEVLADKRQI VDLDTKRNQN REGLRALQKD LSLSEDVMVC FGNMFIKMPH PETKEMIEKD QDHLDKEIEK LRKQLKVKVN RLFEAQGKPE LKGFNLNPLN QDELKALKVI LKG