Recombinant humaan PEA-15-eiwit

Phospho-enriched protein in astrocytes 15 kDa (PEA-15) is a death effector domain (DED) -containing protein predominantly expressed in the central nervous system, particularly in astrocytes. This protein has been implicated in the regulation of multiple cellular processes including apoptosis, proliferation, glucose transport, adhesion and migration. Increased PEA-15 levels may affect tumorigenesis and cancer progression, thus it is overexpressed in breast cancers and gliomas as well as in type 2 diabetes. Recombinant human PEA-15 was expressed in E. coli and purified by using conventional chromatography.

Phosphoprotein enriched in astrocytes 15kD, Astrocytic phosphoprotein PEA-15, PEA15, PED, Phosphoprotein enriched in astrocytes, 15kD Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HuMMAT 1H, HuMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA15 protein, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes.

E.coli

Human

Non-Tagged

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

15 kDa (130aa) confirmed by MALDI-TOF

PEA15, Phosphoprotein enriched in astrocytes 15kD, Astrocytic phosphoprotein PEA-15, PEA15, PED, Phosphoprotein enriched in astrocytes, 15kD Astrocytic phosphoprotein PEA 15, Astrocytic phosphoprotein PEA15, HMAT 1, HMAT1, Homolog of mouse MAT 1 oncogene, Homolog of mouse MAT1 oncogene, HuMMAT 1H, HuMMAT1H, MAT 1, MAT 1H, MAT1, MAT1H, PEA 15, PEA15 protein, Phosphoprotein enriched in astrocytes 15, Phosphoprotein enriched in astrocytes 15kD, Phosphoprotein enriched in diabetes., ATGP0399-10 µg, ATGP0399-20 µg, ATGP0399-50 µg, ATGP0399-100 µg, ATGP0399-250 µg, ATGP0399-500 µg, ATGP0399-1 mg, ATGP0399-10, ATGP0399-20, ATGP0399-50, ATGP0399-100, ATGP0399-250, ATGP0399-500, ATGP0399-1

Beguinot F., et al. (2009) Am J Physiol Endocrinol Metab. 297 (3) :E592-601.; ; ueno NT., et al. (2008) Cancer Res. 68 (22) :9302-10.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 7.5) containing 1mM DTT, 10% glycerol

Neuroscience

NP_003759

Q15121

Human

MAEYGTLLQD LTNNITLEDL EQLKSACKED IPSEKSEEIT TGSAWFSFLE SHNKLDKDNL SYIEHIFEIS RRPDLLTMVV DYRTRVLKIS EEDELDTKLT RIPSAKKYKD IIRQPSEEEI IKLAPPPKKA