Recombinant humaan Pentraxine 3/PTX3-eiwit

Pentraxin 3 (PTX3) is the prototypic member of the long pentraxin family sharing the C-terminal domain with short pentraxins and containing a unique N-terminal domain. Pentraxin 3 is produced and released at inflammatory sites by diverse cell types including monocytes/macrophages, endothelial cells, vascular smooth muscle cells, fibroblasts, and adipocytes. It plays a role in the regulation of innate resistance to pathogens, inflammatory reactions, possibly clearance of self-components and female fertility. Recombinant human Pentraxin 3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

TNFAIP5, TSG-14, Pentraxin 3, AI607804, Pentaxin 3, Pentaxin-related protein PTX3, Pentraxin-related gene, rapidly induced by IL-1 beta, Pentraxin-related gene, PTX3, TSG14, Tumor necrosis factor-inducible gene 14 protein, Tumor necrosis factor-inducible protein TSG-14

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

44.4 kDa (401aa) confirmed by MALDI-TOF

Pentraxin3, TSG1, ATGP0312-10 µg, ATGP0312-20 µg, ATGP0312-50 µg, ATGP0312-100 µg, ATGP0312-250 µg, ATGP0312-500 µg, ATGP0312-1 mg, ATGP0312-10, ATGP0312-20, ATGP0312-50, ATGP0312-100, ATGP0312-250, ATGP0312-500, ATGP0312-1

Imamura M., et al. (2007) . Cell Immunol. 248 (2) :86-94.; ; Allens VV., et al. (1994) . Blood. 84 (10) :3483-93.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Immunology

NP_002843.1

P26022

Human

ENS DDYDLMYVNL DNEIDNGLHP TEDPTPCDCG QEHSEWDKLF IMLENSQMRE RMLLQATDDV LRGELQRLRE ELGRLAESLA RPCAPGAPAE ARLTSALDEL LQATRDAGRR LARMEGAEAQ RPEEAGRALA AVLEELRQTR ADLHAVQGWA ARSWLPAGCE TAILFPMRSK KIFGSVHPVR PMRLESFSAC IWVKATDVLN KTILFSYGTK RNPYEIQLYL SYQSIVFVVG GEENKLVAEA MVSLGRWTHL CGTWNSEEGL TSLWVNGELA ATTVEMATGH IVPEGGILQI GQEKNGCCVG GGFDETLAFS GRLTGFNIWD SVLSNEEIRE TGGAESCHIR GNIVGWGVTE IQPHGGAQYV S