Recombinant humaan Pepsinogeen C/PGC-eiwit

PGC, also known as gastricsin, is an aspartic proteinase that belongs to the peptidase family A1. It is synthesized in the gastric mucosa as inactive precursors. It contains a prosegment that serves to stabilize the inactive form and prevent entry of the substrate to the active site. Serum levels of PGC are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Recombinant human PGC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques

Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

41.6 kDa (380aa)

Pepsinogen PGC, Gastricsin, PGC, PEPC, PGII, Gastricsin, PEPC_HUMAN, pepsin C, Pepsinogen C, pepsinogen group II, PGII, preprogastricsin, Progastricsin, ATGP3385-10 µg, ATGP3385-20 µg, ATGP3385-50 µg, ATGP3385-100 µg, ATGP3385-250 µg, ATGP3385-500 µg, ATGP3385-1 mg, ATGP3385-10, ATGP3385-20, ATGP3385-50, ATGP3385-100, ATGP3385-250, ATGP3385-500, ATGP3385-1

Richter C., et al. (1998) Biochem J. 335:481-490.; ; Westerveld BD., et al. (1987) Gastroenterology. 93:774-778.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Epigenomics (Transcription & Translation)

NP_002621

P20142

Human

Ala17