Recombinant humaan PNOC-eiwit

Prepronociceptin, also known as PNOC, is the ligand of the opioid receptor-like receptor (OPRL1) . It may act as a transmitter in the brain by modulating nociceptive and locomotor behavior. This protein may be involved in neuronal differentiation and development. Recombinant human PNOC protein, fused to His-tag at N-terminus, was expressed in E. coli.

Prepronociceptin, prepronociceptin, PPNOC

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

20.6 kDa (180aa)

PNOC, prepronociceptin, prepronociceptin, PPNOC, ATGP2069-10 µg, ATGP2069-20 µg, ATGP2069-50 µg, ATGP2069-100 µg, ATGP2069-250 µg, ATGP2069-500 µg, ATGP2069-1 mg, ATGP2069-10, ATGP2069-20, ATGP2069-50, ATGP2069-100, ATGP2069-250, ATGP2069-500, ATGP2069-1

Fiset M.E., et al. (2003) Biochemistry. 42:10498-10505; ; Nothacker H.-P., et al. (1996) Proc. Natl. Acad. Sci. u.S.A. 93:8677-8682;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Neuroscience

NP_006219

Q13519

Human

MGSSHHHHHH SSGLVPRGSH MGSSCQRDCL TCQEKLHPAL DSFDLEVCIL ECEEKVFPSP LWTPCTKVMA RSSWQLSPAA PEHVAAALYQ PRASEMQHLR RMPRVRSLFQ EQEEPEPGME EAGEMEQKQL QKRFGGFTGA RKSARKLANQ KRFSEFMRQY LVLSMQSSQR RRTLHQNGNV