Recombinant humaan PRRX1-eiwit

Paired related homeobox 1, also known as PRRX1, acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer. Recombinant human PRRX1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Paired related homeobox 1, AGOTC, PHOX1, PMX1, PRX-1, PRX1

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

26.9 kDa (241aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

PRRX1, Paired related homeobox 1, AGOTC, PHOX1, PMX1, PRX-1, PRX1, ATGP2368-10 µg, ATGP2368-20 µg, ATGP2368-50 µg, ATGP2368-100 µg, ATGP2368-250 µg, ATGP2368-500 µg, ATGP2368-1 mg, ATGP2368-10, ATGP2368-20, ATGP2368-50, ATGP2368-100, ATGP2368-250, ATGP2368-500, ATGP2368-1

Grueneberg D.A., et al. (1992) Science. 257:1089-1095; ; Sergi C., et al. (2011) Clin. Genet. 79:293-295;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT

Epigenomics (Transcription & Translation)

NP_008833

P54821

Human

MTSSYG HVLERQPALG GRLDSPGNLD TLQAKKNFSV SHLLDLEEAG DMVAAQADEN VGEAGRSLLE SPGLTSGSDT PQQDNDQLNS EEKKKRKQRR NRTTFNSSQL QALERVFERT HYPDAFVRED LARRVNLTEA RVQVWFQNRR AKFRRNERAM LANKNASLLK SYSGDVTAVE QPIVPRPAPR PTDYLSWGTA SPYRSSSLPR CCLHEGLHNG F