Recombinant humaan PSG5 eiwit

PSG5 is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSG5 function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. Recombinant human PSG5 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Pregnancy-specific beta-1-glycoprotein 5, FL-NCA-3, PSG

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 80% by SDS-PAGE

36.4 kDa (324aa)

PSG5, Pregnancy-specific beta-1-glycoprotein 5, FL-NCA-3, PSG, ATGP2250-10 µg, ATGP2250-20 µg, ATGP2250-50 µg, ATGP2250-100 µg, ATGP2250-250 µg, ATGP2250-500 µg, ATGP2250-1 mg, ATGP2250-10, ATGP2250-20, ATGP2250-50, ATGP2250-100, ATGP2250-250, ATGP2250-500, ATGP2250-1

Chan W Y., et al. (1991) Mol Cell Biochem.106:161-170; ; Panzetta Dutari G M., et al. (2000) Biochem J. 2:511-519.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol

Other

NP_001123486

Q15238

Human

MGSSHHHHHH SSGLVPRGSH MGSQVTIEAL PPKVSEGKDV LLLVHNLPQN LAGYIWYKGQ LMDLYHYITS YVVDGQINIY GPAYTGRETV YSNASLLIQN VTREDAGSYT LHIIKRGDRT RGVTGYFTFN LYLKLPKPYI TINNSKPREN KDVLAFTCEP KSENYTYIWW LNGQSLPVSP RVKRPIENRI LILPSVTRNE TGPYECEIRD RDGGMRSDPV TLNVLYGPDL PSIYPSFTYY RSGENLYLSC FAESNPPAEY FWTINGKFQQ SGQKLSIPQI TTKHRGLYTC SVRNSATGKE SSKSMTVEVS APSGIGRLPL LNPI