Recombinant humaan PSK1N-eiwit

Members of the subtilisin-like proprotein convertase family process latent precursor proteins into their biologically active products. PCSK1N functions as an inhibitor of prohormone convertase 1, which regulates the proteolytic cleavage of neuroendocrine peptide precursors. Recombinant human PCSK1N protein, fused to His-tag at N-terminus, was expressed in E. coli.

ProSAAS precursor, ProSAAS precursor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS; SAAS

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

26.6 kDa (251aa)

PCSK1N, ProSAAS precursor, ProSAAS precursor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS; SAAS, ATGP2488-10 µg, ATGP2488-20 µg, ATGP2488-50 µg, ATGP2488-100 µg, ATGP2488-250 µg, ATGP2488-500 µg, ATGP2488-1 mg, ATGP2488-10, ATGP2488-20, ATGP2488-50, ATGP2488-100, ATGP2488-250, ATGP2488-500, ATGP2488-1

Fricker L., McKinzie A.A.. et al. (2000) . J. Neurosci. 20:639-648

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing , 10% glycerol, 0.4M urea

Metabolism

NP_037403

Q9UHG2

Human

MGSSHHHHHH SSGLVPRGSH MGSMARPVKE PRGLSAASPP LAETGAPRRF RRSVPRGEAA GAVQELARAL AHLLEAERQE RARAEAQEAE DQQARVLAQL LRVWGAPRNS DPALGLDDDP DAPAAQLARA LLRARLDPAA LAAQLVPAPV PAAALRPRPP VYDDGPAGPD AEEAGDETPD VDPELLRYLL GRILAGSADS EGVAAPRRLR RAADHDVGSE LPPEGVLGAL LRVKRLETPA PQVPARRLLP P