Recombinant humaan PTPN4-eiwit

PTPN4 also known as Protein tyrosine phosphatase, non-receptor type 4, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTPN4 is a widely expressed non-receptor protein tyrosine phosphatase. It has been shown to interact with glutamate receptor delta 2 and epsilon, and may affect glutamate receptors signaling and/or in regulation of their activities through tyrosine dephosphorylation. Recombinant human PTPN4, fused to His-tag at N-terminus, was expressed in E. coli

Protein tyrosine phosphatase non-receptor type 4, Protein tyrosine phosphatase, non-receptor type 4, PTPMEG, PTPMEG1, MEG

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

32 kDa (280aa)

PTPN4, Protein tyrosine phosphatase non-receptor type 4, Protein tyrosine phosphatase, non-receptor type 4, PTPMEG, PTPMEG1, MEG, ATGP3005-10 µg, ATGP3005-20 µg, ATGP3005-50 µg, ATGP3005-100 µg, ATGP3005-250 µg, ATGP3005-500 µg, ATGP3005-1 mg, ATGP3005-10, ATGP3005-20, ATGP3005-50, ATGP3005-100, ATGP3005-250, ATGP3005-500, ATGP3005-1

Babault N., et al. (2011) Structure. 19 (10) :1518-24; ; Zhou J., et al. (2013) Cell Mol Biol Lett. 18 (2) : 297-314.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol

Signal Transduction

NP_002821

P29074

Human

MGSSHHHHHH SSGLVPRGSH MVLTQFDQLY RKKPGMTMSC AKLPQNISKN RYRDISPYDA TRVILKGNED YINANYINME IPSSSIINQY IACQGPLPHT CTDFWQMTWE QGSSMVVMLT TQVERGRVKC HQYWPEPTGS SSYGCYQVTC HSEEGNTAYI FRKMTLFNQE KNESRPLTQI QYIAWPDHGV PDDSSDFLDF VCHVRNKRAG KEEPVVVHCS AGIGRTGVLI TMETAMCLIE CNQPVYPLDI VRTMRDQRAM MIQTPSQYRF VCEAILKVYE