Recombinant humaan PTPN7-eiwit

PTPN7, also known as tyrosine-protein phosphatase non-receptor type 7 isoform 1, acts preferentially on tyrosine-phosphorylated MAPK1. This protein plays a role in the regulation of T and B-lymphocyte development and signal transduction. Recombinant human PTPN7 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Tyrosine-protein phosphatase non-receptor type 7, Tyrosine-protein phosphatase non-receptor type 7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

43.1 kDa (384aa) confirmed by MALDI-TOF

PTPN7, Tyrosine-protein phosphatase non-receptor type 7, Tyrosine-protein phosphatase non-receptor type 7, BPTP-4, HEPTP, LC-PTP, LPTP, PTPNI, ATGP1453-10 µg, ATGP1453-20 µg, ATGP1453-50 µg, ATGP1453-100 µg, ATGP1453-250 µg, ATGP1453-500 µg, ATGP1453-1 mg, ATGP1453-10, ATGP1453-20, ATGP1453-50, ATGP1453-100, ATGP1453-250, ATGP1453-500, ATGP1453-1

Pettiford S.M., et al. (2000) Oncogene. 19:858-869; ; Nika K., et al. (2004) Biochem. J. 378:335-342;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT

Enzymes & Proteases

NP_002823.2

P35236

Human

MVQAHG GRSRAQPLTL SLGAAMTQPP PEKTPAKKHV RLQERRGSNV ALMLDVRSLG AVEPICSVNT PREVTLHFLR TAGHPLTRWA LQRQPPSPKQ LEEEFLKIPS NFVSPEDLDI PGHASKDRYK TILPNPQSRV CLGRAQSQED GDYINANYIR GYDGKEKVYI ATQGPMPNTV SDFWEMVWQE EVSLIVMLTQ LREGKEKCVH YWPTEEETYG PFQIRIQDMK ECPEYTVRQL TIQYQEERRS VKHILFSAWP DHQTPESAGP LLRLVAEVEE SPETAAHPGP IVVHCSAGIG RTGCFIATRI GCQQLKARGE VDILGIVCQL RLDRGGMIQT AEQYQFLHHT LALYAGQLPE EPSP