Recombinant humaan RAB10-eiwit

RAB10 is a member of the Ras superfamily of small GTP-binding proteins. This protein is a key regulator of endocytic recycling, especially in the basolateral recycling pathways of polarized epithelial cells. It is required for the recruitment of CNT-1 to endosomal membranes in the intestinal epithelium. Recombinant human RAB10 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Ras-related GTP-binding protein RAB10, RAB10, RAB10 member RAS oncogene family, Ras-related protein Rab-10

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

24.7 kDa (220aa)

RAB10, ATGP1963-10 µg, ATGP1963-20 µg, ATGP1963-50 µg, ATGP1963-100 µg, ATGP1963-250 µg, ATGP1963-500 µg, ATGP1963-1 mg, ATGP1963-10, ATGP1963-20, ATGP1963-50, ATGP1963-100, ATGP1963-250, ATGP1963-500, ATGP1963-1

Chen Y. et al. (2012) J Cell Biol. 198:545-560.; ; Sano H. et al. (2011) J Biol Chem. 286:16541-16545.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Signal Transduction

NP_057215.3

P61026

Human

MAKKTYDLLF KLLLIGDSGV GKTCVLFRFS DDAFNTTFIS TIGIDFKIKT VELQGKKIKL QIWDTAGQER FHTITTSYYR GAMGIMLVYD ITNGKSFENI SKWLRNIDEH ANEDVERMLL GNKCDMDDKR VVPKGKGEQI AREHGIRFFE TSAKANINIE KAFLTLAEDI LRKTPVKEPN SENVDISSGG GVTGWKSKCC