Recombinant humaan RAB3IL-eiwit

Guanine nucleotide exchange factor for Rab-3A isoform 1, also known as RAB3IL, is a 382 amino acid protein that belongs to the SEC2 family. RAB3IL1 is a guanine nucleotide exchange factor (GEF) for Rab3A. RAB3IL1 competes for an interaction with Rab3A and IHPK1 through its coiled coil domain, which does not require IHPK1 kinase activity. Recombinant human RAB3IL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

RAB3A interacting protein like 1, Rabin3-like 1, Guanine nucleotide exchange factor for Rab-3A, GRAB

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

45 kDa (405aa) confirmed by MALDI-TOF

RAB3IL, Guanine nucleotide exchange factor for Rab-3A isoform 1, GRAB, ATGP2908-10 µg, ATGP2908-20 µg, ATGP2908-50 µg, ATGP2908-100 µg, ATGP2908-250 µg, ATGP2908-500 µg, ATGP2908-1 mg, ATGP2908-10, ATGP2908-20, ATGP2908-50, ATGP2908-100, ATGP2908-250, ATGP2908-500, ATGP2908-1

Luo H R., et al. (2001) Neuron. 31: 439-451.; ; Rual J F., et al. (2005) Nature. 437: 1173-1178.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 50% glycerol

Signal Transduction

NP_037533

Q8TBN0

Human

MGSSHHHHHH SSGLVPRGSH MGSMWSGPPQ PDQGLPPPLA AVPVPWKSTD PCQGHRESPG ALVETSAGEE AQGQEGPAAA QLDVLRLRSS SMEIREKGSE FLKEELHRAQ KELKLKDEEC ERLSKVREQL EQELEELTAS LFEEAHKMVR EANMKQAASE KQLKEARGKI DMLQAEVTAL KTLVITSTPA SPNRELHPQL LSPTKAGPRK GHSRHKSTSS TLCPAVCPAA GHTLTPDREG KEVDTILFAE FQAWRESPTL DKTCPFLERV YREDVGPCLD FTMQELSVLV RAAVEDNTLT IEPVASQTLP TVKVAEVDCS STNTCALSGL TRTCRHRIRL GDSKSHYYIS PSSRARITAV CNFFTYIRYI QQGLVRQDAE PMFWEIMRLR KEMSLAKLGF FPQEA