Recombinant humaan RAB4A-eiwit

RAB4A belongs to the small GTPase superfamily. RAB4A has been shown to interact with STX4, RAB11FIP1, RABEP1, CD2AP and KIF3B. Rab4 is also involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Overexpression of Rab4 causes a redistribution of receptors on plasma membrane versus endocytic compartments. Recombinant human RAB4A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Ras-related protein Rab-4A, HRES-1/RAB4, RAB4, RAB4A member RAS oncogene family

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

26.5 kDa (238aa) confirmed by MALDI-TOF

RAB4A, Ras-related protein Rab-4A, HRES-1/RAB4, RAB4, ATGP1104-10 µg, ATGP1104-20 µg, ATGP1104-50 µg, ATGP1104-100 µg, ATGP1104-250 µg, ATGP1104-500 µg, ATGP1104-1 mg, ATGP1104-10, ATGP1104-20, ATGP1104-50, ATGP1104-100, ATGP1104-250, ATGP1104-500, ATGP1104-1

Li L. et al. (2001) J Biol Chem. 276:5265-73.; ; Lindsay AJ.. et al. (2002) J Biol Chem. 277:12190-9.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol 0.1M NaCl,1mM DTT

Cancer

NP_004569

P20338

Human

MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC