Recombinant humaan RAC3-eiwit

RAC3 is a member of the Rac subfamily of the Rho small G proteins. This protein is a small (~21 kDa) monomeric GTP-binding protein, and is an important component of intracellular signalling pathway, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Recombinant human RAC3 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Ras-related C3 botulinum toxin substrate 3, p21-Rac3, Rac1B, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, rho family small GTP binding protein Rac3, Rho family small GTP binding protein Rac3, RP23-84C12.18

E.coli

Human

Non-Tagged

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

21 kDa (189aa) confirmed by MALDI-TOF

RAC3, ras-related C3 botulinum toxin substrate 3, p21-Rac3, Rac1B, RAS related C3 botulinum substrate 3, Ras related C3 botulinum toxin substrate 3, rho family small GTP binding protein Rac3, Rho family small GTP binding protein Rac3, RP23-84C12.18, ATGP0843-10 µg, ATGP0843-20 µg, ATGP0843-50 µg, ATGP0843-100 µg, ATGP0843-250 µg, ATGP0843-500 µg, ATGP0843-1 mg, ATGP0843-10, ATGP0843-20, ATGP0843-50, ATGP0843-100, ATGP0843-250, ATGP0843-500, ATGP0843-1

De Langhe S., et al. (2002) Int. J. Mol. Med. 9:451-459; ; Haataja L, et al. (1997) J. Biol. Chem. 272 (33) : 20384-88.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 200 mM NaCl, 0.1mM PMSF, 1mM EDTA

Signal Transduction

NP_005043

P60763

Human

MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKPGKKC