Recombinant humaan RAMP3-eiwit
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
RAMP3, also known as receptor activity modifying protein 3, is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs) . It is required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR can function as either a calcitonin gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP3) protein, CRLR functions as an adrenomedullin receptor. Recombinant human RAMP3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Receptor activity modifying protein 3, Receptor (calcitonin) activity modifying protein 3
E.coli
Human
His-Tag
SDS-PAGE
0.5 mg/mL (determined by Bradford assay)
> 90% by SDS-PAGE
13.0 kDa (116aa) confirmed by MALDI-TOF
RAMP3, Receptor activity modifying protein 3, Receptor (calcitonin) activity modifying protein 3, ATGP1970-10 µg, ATGP1970-20 µg, ATGP1970-50 µg, ATGP1970-100 µg, ATGP1970-250 µg, ATGP1970-500 µg, ATGP1970-1 mg, ATGP1970-10, ATGP1970-20, ATGP1970-50, ATGP1970-100, ATGP1970-250, ATGP1970-500, ATGP1970-1
Kuwasako K. et al. (2008) Biochem Biophys Res Commun. 377:109-113.; ; Roh J. et al. (2004) J Biol Chem. 279:7264-7274;
Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl
Signal Transduction
NP_005847
O60896
Human
RAGGCNETG MLERLPLCGK AFADMMGKVD VWKWCNLSEF IVYYESFTNC TEMEANVVGC YWPNPLAQGF ITGIHRQFFS NCTVDRVHLE DPPDEV
Beschrijving
RAMP3, also known as receptor activity modifying protein 3, is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin)
Specificaties
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