Recombinant humaan RARRES1-eiwit

Retinoic acid receptor responder protein 1 isoform 1, also known as RARRES1, belongs to the TIGs (Tazarotene-induced gene) family. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. Recombinant human RARRES1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Retinoic acid receptor responder protein 1 isoform 1, TIG1

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

31.3 kDa (275aa)

RARRES1, Retinoic acid receptor responder protein 1 isoform 1, TIG1, ATGP2157-10 µg, ATGP2157-20 µg, ATGP2157-50 µg, ATGP2157-100 µg, ATGP2157-250 µg, ATGP2157-500 µg, ATGP2157-1 mg, ATGP2157-10, ATGP2157-20, ATGP2157-50, ATGP2157-100, ATGP2157-250, ATGP2157-500, ATGP2157-1

Kwong J., et al. (2005) J Cancer. 113:386-392.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Cancer

NP_996846

P49788

Human

MGSSHHHHHH SSGLVPRGSH MGSPDDPGQP QDAGVPRRLL QQAARAALHF FNFRSGSPSA LRVLAEVQEG RAWINPKEGC KVHVVFSTER YNPESLLQEG EGRLGKCSAR VFFKNQKPRP TINVTCTRLI EKKKRQQEDY LLYKQMKQLK NPLEIVSIPD NHGHIDPSLR LIWDLAFLGS SYVMWEMTTQ VSHYYLAQLT SVRQWKTNDD TIDFDYTVLL HELSTQEIIP CRIHLVWYPG KPLKVKYHCQ ELQTPEEASG TEEGSAVVPT ELSNF