Recombinant humaan Reg4-eiwit

Reg4, also known regenerating islet-derived protein 4, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily. It is calcium-independent lectin displaying mannose-binding specificity and able to maintain carbohydrate recognition activity in an acidic environment. This protein is involved in inflammatory and metaplastic responses because expression of this protein is increased within or near inflammation, dysplasia and metaplasia of the GI epithelium. And this protein is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Recombinant human Reg4 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Regenerating islet-derived protein 4 isoform 1, REG4, GISP, REG-IV, RELP

Baculovirus

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

17 kDa (145aa)

Reg4, Reg4Regenerating islet-derived protein 4 isoform 1, REG4, GISP, REG-IV, RELP, ATGP3854-10 µg, ATGP3854-20 µg, ATGP3854-50 µg, ATGP3854-100 µg, ATGP3854-250 µg, ATGP3854-500 µg, ATGP3854-1 mg, ATGP3854-10, ATGP3854-20, ATGP3854-50, ATGP3854-100, ATGP3854-250, ATGP3854-500, ATGP3854-1

Kawasaki Y., et al, (2015) Sci Rep. 5:14291.; ; Jin J., et al, (2017) Med Sci Monit. 23:3715-3721.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Immunology

NP_114433

Q9BYZ8

Human

Ala

DIIMRPS CAPGWFYHKS NCYGYFRKLR NWSDAELECQ SYGNGAHLAS ILSLKEASTI AEYISGYQRS QPIWIGLHDP QKRQQWQWID GAMYLYRSWS GKSMGGNKHC AEMSSNNNFL TWSSNECNKR QHFLCKYRP