Recombinant humaan Relaxine-2-eiwit

RLN2, as known as prorelaxin H2 isoform 1, belongs to the insulin gene superfamily. This family is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. It is 18 kDa in size and 185 aa in length. It contains a 24 aa signal sequence, a 3. 3 kDa, 29 aa B domain, a 106 aa C (or connecting) domain, and a C-terminal, 2. 7 kDa, 24 aa A domain. Recombinant human RLN2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Prorelaxin H2 isoform 1, RLN2, bA12D24.1.1, bA12D24.1.2, H2, H2-RLX, RLXH2

Baculovirus

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 85% by SDS-PAGE

19.3 kDa (170aa)

Relaxin2, Prorelaxin H2 isoform 1, RLN2, bA12D24.1.1, bA12D24.1.2, H2, H2-RLX, RLXH2, ATGP3545-10 µg, ATGP3545-20 µg, ATGP3545-50 µg, ATGP3545-100 µg, ATGP3545-250 µg, ATGP3545-500 µg, ATGP3545-1 mg, ATGP3545-10, ATGP3545-20, ATGP3545-50, ATGP3545-100, ATGP3545-250, ATGP3545-500, ATGP3545-1

Ng TM., et al, (2016) Cardiol Rev. 24:194-204.; ; Sherwood OD., et al, (2004) Endocr. Rev. 25:205-234.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_604390

P04090

Human

Ala

ADPDSWMEEV IKLCGRELVR AQIAICGMST WSKRSLSQED APQTPRPVAE IVPSFINKDT ETINMMSEFV ANLPQELKLT LSEMQPALPQ LQQHVPVLKD SSLLFEEFKK LIRNRQSEAA DSSPSELKYL GLDTHSRKKR QLYSALANKC CHVGCTKRSL ARFCHHHHHH