Recombinant humaan RELT/TNFRSF19L-eiwit

RELT, also known tumor necrosis factor receptor superfamily member 19L, is one of the the tumor necrosis factor receptor superfamily. It is expressed in hematopoietic tissues and peripheral blood leukocytes. This protein mediates activation of NF-kappa-B and plays a role in T-cell activation. With overexpression of this protein in HEK-293 cells, it induces p38 and JNK signaling and activates apoptosis. And it can also costimulate T-cell proliferation in the presence of CD3 signaling. Recombinant human RELT protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Tumor necrosis factor receptor superfamily member 19L, RELT, TNFRSF19L, TRLT, RELT tumor necrosis factor receptor, Receptor expressed in Lymphoid tissues

Baculovirus

Human

HIgG-His-Tag

SDS-PAGE

0.5 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 90% by SDS-PAGE

41.4 kDa (376aa)

RELT, TNFRSF19L, RELT/TNFRSF19LTumor necrosis factor receptor superfamily member 19L, RELT, TNFRSF19L, TRLT, ATGP3847-10 µg, ATGP3847-20 µg, ATGP3847-50 µg, ATGP3847-100 µg, ATGP3847-250 µg, ATGP3847-500 µg, ATGP3847-1 mg, ATGP3847-10, ATGP3847-20, ATGP3847-50, ATGP3847-100, ATGP3847-250, ATGP3847-500, ATGP3847-1

Cusick JK., et al, (2010) Cell Immunol. 261:1-8.; ; Moua P., et al, (2017) Biochem Biophys Res Commun. 491:25-32.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Signal Transduction

NP_689408

Q969Z4

Human

Ser26

STTLWQCPPG EEPDLDPGQG TLCRPCPPGT FSAAWGSSPC QPHARCSLWR RLEAQVGMAT RDTLCGDCWP GWFGPWGVPR VPCQPCSWAPLGTHGCDEWG RRARRGVEVA AGASSGGETR QPGNGTRAGG PEETAAQVEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSRDE LTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH