Recombinant humaan REM2 en RAB-achtige kleine GTPase 1

Source : Escherichia Coli. RSG1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 281 amino acids (1-258 a.a) and having a molecular mass of 30.9kDa.RSG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. REM2 and RAB-Like Small GTPase 1 (RSG1) plays a part in targeted membrane trafficking most likely at the level of vesicle fusion with membranes. The RSG1 protein is involved in cilium biogenesis by regulating the transportation of cargo proteins to the basal body and to the apical tips of cilia. RSG1 is a potential effector of the planar cell polarity signaling pathway. RSG1 is also involved in exocytosis in secretory cells.

REM2- and Rab-like small GTPase 1||RSG1||C1orf89||RP4-733M16.4.

Greater than 85.0% as determined by SDS-PAGE.

RSG1 protein solution (0.25mg/mL) containing 20mM Tris-HCl buffer (pH 8.5), 0.2M NaCl, 50% glycerol and 2mM DTT.

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA) .Avoid multiple freeze-thaw cycles.

MGSSHHHHHH SSGLVPRGSH MGSMARPPVP GSVVVPNWHE SAEGKEYLAC ILRKNRRRVF GLLERPVLLP PVSIDTASYK IFVSGKSGVG KTALVAKLAG LEVPVVHHET TGIQTTVVFW PAKLQASSRV VMFRFEFWDC GESALKKFDH MLLACMENTD AFLFLFSFTD RASFEDLPGQ LARIAGEAPG VVRMVIGSKF DQYMHTDVPE RDLTAFRQAW ELPLLRVKSV PGRRLADGRT LDGRAGLADV AHILNGLAEQ LWHQDQVAAG LLPNPPESAP E.