Recombinant humaan Renalase-eiwit

Renalase, also known as RNLS, is a flavin adenine dinucleotide-dependent amine oxidase that is secreted into the blood from the kidney. It is also suggested that RNLS functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. A high concentration of catecholamines activate plasma RNLS and promotes its secretion and synthesis. Recombinant human RNLS protein, fused to His-tag at N-terminus, was expressed in E. coli.

Renalase, C10orf59, RENALASE

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

38.8 kDa (349aa)

Renalase, Renalase, C10orf59, RENALASE, ATGP1732-10 µg, ATGP1732-20 µg, ATGP1732-50 µg, ATGP1732-100 µg, ATGP1732-250 µg, ATGP1732-500 µg, ATGP1732-1 mg, ATGP1732-10, ATGP1732-20, ATGP1732-50, ATGP1732-100, ATGP1732-250, ATGP1732-500, ATGP1732-1

Xu J., et al. (2007) Curr Poin Nephol Hypertens. 16:373-378.; ; Li G., et al. (2008) Circulation. 117:1277-1282.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol

Neuroscience

NP_001026879

Q5VYX0

Human

ALLRRQ TSGPLYLAVW DKAEDSGGRM TTACSPHNPQ CTADLGAQYI TCTPHYAKKH QRFYDELLAY GVLRPLSSPI EGMVMKEGDC NFVAPQGISS IIKHYLKESG AEVYFRHRVT QINLRDDKWE VSKQTGSPEQ FDLIVLTMPV PEILQLQGDI TTLISECQRQ QLEAVSYSSR YALGLFYEAG TKIDVPWAGQ YITSNPCIRF VSIDNKKRNI ESSEIGPSLV IHTTVPFGVT YLEHSIEDVQ ELVFQQLENI LPGLPQPIAT KCQKWRHSQV TNAAANCPGQ MTLHHKPFLA CGGDGFTQSN FDGCITSALC VLEALKNYI