Recombinant humaan Resistine/RETN-eiwit

RETN belongs to the family defined by the mouse resistin-like genes. The characteristic feature of this family is the C-terminal stretch of 10 cys residues with identical spacing. The mouse homolog of this protein is secreted by adipocytes, and may be the hormone potentially linking obesity to type II diabetes. Alternatively spliced transcript variants encoding the same protein have been found for this gene. Recombinant human RETN protein, fused to His-tag at N-terminus, was expressed in E. coli.

Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, RSTN

E.coli

Human

His-Tag

SDS-PAGE, Denatured

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

11.8 kDa (111aa)

Adipose tissue-specific secretory factor, ADSF, C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein, Cysteine-rich secreted protein A12-alpha-like 2, Cysteine-rich secreted protein FIZZ3, FIZZ3, HXCP1, MGC126603, MGC126609, Resistin, RETN1, RSTN, XCP1, ATGP2510-10 µg, ATGP2510-20 µg, ATGP2510-50 µg, ATGP2510-100 µg, ATGP2510-250 µg, ATGP2510-500 µg, ATGP2510-1 mg, ATGP2510-010, ATGP2510-020, ATGP2510-050, ATGP2510-100, ATGP2510-250, ATGP2510-500, ATGP2510-01M

Steppan C.M., et al. (2001) Nature. 409:307-312; ; Holcomb I.N., et al. (2000) EMBO J. 19:4046-4055

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Metabolism

NP_065148

Q9HD89

Human

MGSSHHHHHH SSGLVPRGSH MKTLCSMEEA INERIQEVAG SLIFRAISSI GLECQSVTSR GDLATCPRGF AVTGCTCGSA CGSWDVRAET TCHCQCAGMD WTGARCCRVQ P