Recombinant humaan Retinol Bindeiwit 1/RBP1-eiwit

RBP1 (Retinol binding protein 1) belongs to the calycin superfamily and fatty-acid binding protein (FABP) family. RBP1 is the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. RBP1 can also act as a bridging molecule to recruit histone deacetylases (HDACs), proteins that function as potent regulators of gene expression. This protein is detected in nearly all the tissues with higher expression in adult ovary, pancreas, pituitary gland and adrenal gland, and fetal liver. Recombinant human RBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Retinol binding protein 1, RBPC, CRABP-I, CRBPI, CRBP, CRBP1, Cellular retinol binding protein 1

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.7 kDa (220aa) confirmed by MALDI-TOF

RBP1, retinol binding protein 1, CRABP-I, CRBP, CRBP1, CRBPI, RBPC, ATGP1303-10 µg, ATGP1303-20 µg, ATGP1303-50 µg, ATGP1303-100 µg, ATGP1303-250 µg, ATGP1303-500 µg, ATGP1303-1 mg, ATGP1303-10, ATGP1303-20, ATGP1303-50, ATGP1303-100, ATGP1303-250, ATGP1303-500, ATGP1303-1

Lai, A., et al. (2001) Mol. Cell. Biol. 21: 2918-2932.; ; Folli C., et al. (2001) Proc. Natl. Acad. Sci. u.S.A. 98:3710-3715

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 200 mM NaCl

Signal Transduction

NP_002890

P09455

Human

MDPPAGF VRAGNPAVAA PQSPLSPEGA HFRAAHHPRS TGSRCPGSLQ PSRPLVANWL QSLPEMPVDF TGYWKMLVNE NFEEYLRALD VNVALRKIAN LLKPDKEIVQ DGDHMIIRTL STFRNYIMDF QVGKEFEEDL TGIDDRKCMT TVSWDGDKLQ CVQKGEKEGR GWTQWIEGDE LHLEMRVEGV VCKQVFKKVQ