Recombinant humaan RGS16-eiwit

RGS16, also known as regulator of G-protein signaling 16, belongs to 'regulator of G protein signaling' family and negatively regulates G protein coupled receptor signalling. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP bound form. It also may play a role in regulating the kinetics of signaling in the phototransduction cascade. Recombinant RGS16 protein was expressed in E. coli and purified by using conventional chromatography techniques.

Regulator of G-protein signaling 16, A28-RGS14, A28-RGS14P, RGS-R, Regulator of G-protein signaling 16 A28 RGS14, A28 RGS14P, HGNC:9997, Regulator of G protein signaling 16, Retinally abundant regulator of G protein signaling, RGS 16 RGS R, Rgs14, RGSR.

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

24.9 kDa (222aa) confirmed by MALDI-TOF

RGS16, Regulator of G-protein signaling 16, A28-RGS14, A28-RGS14P, RGS-R, Regulator of G-protein signaling 16 A28 RGS14, A28 RGS14P, HGNC:9997, Regulator of G protein signaling 16, Retinally abundant regulator of G protein signaling, RGS 16 RGS R, Rgs14, RGSR., ATGP0499-10 µg, ATGP0499-20 µg, ATGP0499-50 µg, ATGP0499-100 µg, ATGP0499-250 µg, ATGP0499-500 µg, ATGP0499-1 mg, ATGP0499-10, ATGP0499-20, ATGP0499-50, ATGP0499-100, ATGP0499-250, ATGP0499-500, ATGP0499-1

Chen C., et al. (1997) J Biol Chem. 272 (13) :8679-85; ; Derrien A., et al. (2001) J Biol Chem. 276 (51) :48532-8;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl

Signal Transduction

AAH06243

O15492

Human

MCRTLAAFPT TCLERAKEFK TRLGIFLHKS ELGCDTGSTG KFEWGSKHSK ENRNFSEDVL GWRESFDLLL SSKNGVAAFH AFLKTEFSEE NLEFWLACEE FKKIRSATKL ASRAHQIFEE FICSEAPKEV NIDHETRELT RMNLQTATAT CFDAAQGKTR TLMEKDSYPR FLKSPAYRDL AAQASAASAT LSSCSLDEPS HT