Recombinant humaan RPS19-eiwit

RPS19 belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. Recombinant human RPS19 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

40S ribosomal protein S19, ribosomal protein S19, DBA, DBA1, S19

E.coli

Human

His-Tag

SDS-PAGE

0.25 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

18.4 kDa (168aa) confirmed by MALDI-TOF

RPS19, 40S ribosomal protein S19, ribosomal protein S19, DBA, DBA1, S19, ATGP2193-10 µg, ATGP2193-20 µg, ATGP2193-50 µg, ATGP2193-100 µg, ATGP2193-250 µg, ATGP2193-500 µg, ATGP2193-1 mg, ATGP2193-10, ATGP2193-20, ATGP2193-50, ATGP2193-100, ATGP2193-250, ATGP2193-500, ATGP2193-1

Kenmochi N, Kawaguchi T, Rozen S, et al. (1998) Genome Res 8 (5) : 509-23.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT

Epigenomics (Transcription & Translation)

NP_001013.1

P39019

Human

MPGVTVK DVNQQEFVRA LAAFLKKSGK LKVPEWVDTV KLAKHKELAP YDENWFYTRA ASTARHLYLR GGAGVGSMTK IYGGRQRNGV MPSHFSRGSK SVARRVLQAL EGLKMVEKDQ DGGRKLTPQG QRDLDRIAGQ VAAANKKH