Recombinant humaan RRM2-eiwit

RRM2, also known as ribonucleotide reductase M2, is an enzyme that catalyzes the formation of deoxyribonucleotides from ribonucleotides. This protein plays a critical role in regulating the total rate of DNA synthesis so that DNA to cell mass is maintained at a constant ratio during cell division and DNA repair. Recombinant human RRM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques

Ribonucleoside-diphosphate reductase subunit M2, R2, RR2, RR2M, Ribonucleoside-diphosphate reductase subunit M2 Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small subunit

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

47 kDa (409aa) confirmed by MALDI-TOF

RRM2, Ribonucleoside-diphosphate reductase subunit M2, R2, RR2, RR2M, Ribonucleoside-diphosphate reductase subunit M2 Ribonucleotide reductase M2 subunit, Ribonucleotide reductase small subunit, ATGP0582-10 µg, ATGP0582-20 µg, ATGP0582-50 µg, ATGP0582-100 µg, ATGP0582-250 µg, ATGP0582-500 µg, ATGP0582-1 mg, ATGP0582-10, ATGP0582-20, ATGP0582-50, ATGP0582-100, ATGP0582-250, ATGP0582-500, ATGP0582-1

Torrents E, et al. (2002) J Mol Evol. 55 (2) :138-52; ; Herrick J, et al. (2007) Mol Microbiol. 63 (1) :22-34;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Enzymes & Proteases

NP_001025.1

P31350

Human

MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDE PLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYFISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRG LMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEFLTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF