Recombinant humaan S100A9-eiwit

S100-A9, also known as Calgranulin B, belongs to the S100 family containing EF-hand type Ca2+-binding proteins. It is involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation, and associated with the disease cystic fibrosis. S100A9 has been implicated in the abnormal differentiation of myeloid cells in the stroma of cancer. This protein may function in the inhibition of casein kinase. Recombinant S100A9 protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein S100-A9, Calgranulin B, 60B8AG, CAGB, CFAG, CGLB, L1AG, LIAG, MAC387, MIF, MRP14, NIF, P14, Protein S100-A9 AI323541, B8Ag, BEE11, CAGA, Calgranulin-A, Calprotectin L1L subunit, Calprotectin, included, CGLA, Chemotactic cytokine CP-10, CP-10, Cystic fibrosis antigen, Leukocyte L1 complex light chain MA387, MIF, Migration inhibitory factor-related protein 8, Myeloid-related protein 8, Neutrophil cytosolic 7 kDa protein, NIF, p8, Pro-inflammatory S100 cytokine, Protein S100-A8, S100 calcium binding protein A8, S100 calcium binding protein A8 (calgranulin A), S100A8, S100A8/S100A9 complex, included, urinary stone protein band A.

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

14.3 kDa (122aa) confirmed by MALDI-TOF

S100A9, ATGP0543-10 µg, ATGP0543-20 µg, ATGP0543-50 µg, ATGP0543-100 µg, ATGP0543-250 µg, ATGP0543-500 µg, ATGP0543-1 mg, ATGP0543-10, ATGP0543-20, ATGP0543-50, ATGP0543-100, ATGP0543-250, ATGP0543-500, ATGP0543-1

Schafer BW. et al. (1996) Trends Biochem Sci. 21 (4) :134-40.; ; Nacken W, .et al. (2003) Microsc Res Tech. 60 (6) :569-80.;

Kwon CH, et al. S100A8 and S100A9 Promotes Invasion and Migration through p38 Mitogen-Activated Protein kinase-Dependent NF-kB Activation in Gastric Cancer Cells. (Mol Cells. 2013) {https://pubmed.ncbi.nlm.nih.gov/23456298/}; ; Nishikawa Y, et al. Calprotectin Induces IL-6 and MCP-1 Production via Toll-Like Receptor 4 Signaling in Human Gingival Fibroblasts. (J Cell Physiol. 2017) {https://pubmed.ncbi.nlm.nih.gov/27925202/}; ; Suzuki S, et al. CD147 expression correlates with lymph node metastasis in T1-T2 squamous cell carcinoma of the tongue. (Oncol Lett. 2017) {https://pubmed.ncbi.nlm.nih.gov/29085466/}; ; {}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.1M NaCl

Cancer

NP_002956.1

P06702

Human