Recombinant humaan S100P-eiwit

S100P is a Ca2+ binding protein that belongs to S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100P is involved in diverse biological functions but the exact role or mechanism of its action is still largely unknown. upon binding of calcium ions S100P undergoes a conformational change that results in an exposure of a hydrophobic surface which allows the interaction with specific target proteins. Recombinant human S100P protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

S100 calcium binding protein P, S100E, S100 calcium binding protein P MIG9, Migration inducing gene 9, Protein S100P, S100 calcium binding protein P, S100 P.

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by BCA assay)

> 90% by SDS-PAGE

12.6 kDa (115aa) confirmed by MALDI-TOF

S100P, S100 calcium binding protein P, S100E, S100 calcium binding protein P MIG9, Migration inducing gene 9, Protein S100P, S100 calcium binding protein P, S100 P., ATGP0565-10 µg, ATGP0565-20 µg, ATGP0565-50 µg, ATGP0565-100 µg, ATGP0565-250 µg, ATGP0565-500 µg, ATGP0565-1 mg, ATGP0565-10, ATGP0565-20, ATGP0565-50, ATGP0565-100, ATGP0565-250, ATGP0565-500, ATGP0565-1

Dowen S.E., et al (2005) Am. J. Pathol. 166:81-92; ; Koltzscher M, et al (2003) Mol Biol Cell. 14 (6) :2372-84;

Chiba M, et al. Novel quantitative analysis of the S100P protein combined with endoscopic ultrasound-guided fine needle aspiration cytology in the diagnosis of pancreatic adenocarcinoma. (Oncol Rep. 2017) {https://pubmed.ncbi.nlm.nih.gov/28260012/}

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 50 mM NaCl

Cancer

NP_005971.1

P25815

Human

MTELETAMGM IIDVFSRYSG SEGSTQTLTK GELKVLMEKE LPGFLQSGKD KDAVDKLLKD LDANGDAQVD FSEFIVFVAA ITSACHKYFE KAGLK