Recombinant humaan S100Z-eiwit

S100 calcium binding protein Z, also known as S100Z, is member of the S100 protein family. S100 proteins are small dimeric members of the EF-hand superfamily of Ca (2+) binding proteins thought to participate in mediating intracellular Ca (2+) signals by binding to and thereby regulating target proteins in a Ca (2+) -dependent manner. There are differences in the expression level of S100Z mRNA in various tissues. The highest levels were found in spleen and leukocytes. S100Z gene expression appears to be deregulated in some tumor tissues, compared to expression in their normal counterparts. Recombinant human S100Z, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Protein S100-Z, S100-zeta, Protein S100-Z Gm625, Protein S100 Z, S100 calcium binding protein Z, S100 calcium binding protein zeta.

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

13.7 kDa (119aa) confirmed by MALDI-TOF

S100Z, Protein S100-Z, S100-zeta, Protein S100-Z Gm625, Protein S100 Z, S100 calcium binding protein Z, S100 calcium binding protein zeta., ATGP0588-10 µg, ATGP0588-20 µg, ATGP0588-50 µg, ATGP0588-100 µg, ATGP0588-250 µg, ATGP0588-500 µg, ATGP0588-1 mg, ATGP0588-10, ATGP0588-20, ATGP0588-50, ATGP0588-100, ATGP0588-250, ATGP0588-500, ATGP0588-1

Zhou Y., et al. (2006) Proteins. 65 (3) :643-55.; ; Hoque CW., et al. (1992) J Biol Chem. 267 (19) :13340-7.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 1mM EDTA, 50 mM NaCl

Signal Transduction

NP_570128

Q8WXG8

Human

MGSSHHHHHH SSGLVPRGSH MPTQLEMAMD TMIRIFHRYS GKERKRFKLS KGELKLLLQR ELTEFLSCQK ETQLVDKIVQ DLDANKDNEV DFNEFVVMVA ALTVACNDYF VEQLKKKGK