Recombinant humaan SCG3-eiwit

SCG3 is a member of the chromogranin/secretogranin family of neuroendocrine secretory proteins. Granins may serve as precursors for biologically active peptides. Some granins have been shown to function as helper proteins in sorting and proteolytic processing of prohormones; however, the function of this protein is unknown. Recombinant human SCG3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Secretogranin-3 isoform 1, SGIII

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

53 kDa (472aa)

SCG3, Secretogranin-3 isoform 1, SGIII, ATGP2213-10 µg, ATGP2213-20 µg, ATGP2213-50 µg, ATGP2213-100 µg, ATGP2213-250 µg, ATGP2213-500 µg, ATGP2213-1 mg, ATGP2213-10, ATGP2213-20, ATGP2213-50, ATGP2213-100, ATGP2213-250, ATGP2213-500, ATGP2213-1

Tanabe A, Yanagiya T, et al. (2007) . J Clin Endocrinol Metab. 92 (3) :1145-54. ; ; Hosaka M, Suda M, et al. (2004) . J Biol Chem. 279 (5) :3627-34.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT

Neuroscience

NP_037375

Q8WXD2

Human

FPKPGGS QDKSLHNREL SAERPLNEQI AEAEEDKIKK TYPPENKPGQ SNYSFVDNLN LLKAITEKEK IEKERQSIRS SPLDNKLNVE DVDSTKNRKL IDDYDSTKSG LDHKFQDDPD GLHQLDGTPL TAEDIVHKIA ARIYEENDRA VFDKIVSKLL NLGLITESQA HTLEDEVAEV LQKLISKEAN NYEEDPNKPT SWTENQAGKI PEKVTPMAAI QDGLAKGEND ETVSNTLTLT NGLERRTKTY SEDNFEELQY FPNFYALLKS IDSEKEAKEK ETLITIMKTL IDFVKMMVKY GTISPEEGVS YLENLDEMIA LQTKNKLEKN ATDNISKLFP APSEKSHEET DSTKEEAAKM EKEYGSLKDS TKDDNSNPGG KTDEPKGKTE AYLEAIRKNI EWLKKHDKKG NKEDYDLSKM RDFINKQADA YVEKGILDKE EAEAIKRIYS SL