Recombinant humaan SCN3B-eiwit

SCN3B, also known as sodium channel subunit beta-3, is an additional auxiliary subunit of the voltage-sensitive sodium channel that modulates channel gating with distinct kinetics. It was detected in brain, heart, kidney, lung, pancreas and skeletal muscle. It is expressed in adult mammalian skeletal muscle and can functionally couple to the skeletal muscle alpha subunit, SkM1. It associates with neurofascin through their extracellular immunoglobulin-like domain. Recombinant human SCN3B, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Sodium channel subunit beta-3, SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3

Baculovirus

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by absorbance at 280 nm)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

16.8 kDa (146aa)

SCN3B, Sodium channel subunit beta-3, SCN3B, ATFB16, BRGDA7, HSA243396, SCNB3, ATGP3521-10 µg, ATGP3521-20 µg, ATGP3521-50 µg, ATGP3521-100 µg, ATGP3521-250 µg, ATGP3521-500 µg, ATGP3521-1 mg, ATGP3521-10, ATGP3521-20, ATGP3521-50, ATGP3521-100, ATGP3521-250, ATGP3521-500, ATGP3521-1

Stevens EB., et al. (2001) Pflugers Arch. 441:481-488.; ; Ratcliffe CF., et al. (2001) J Cell Biol. 154:427-434.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Apoptosis

NP_060870

Q9NY72

Human

Ala

ADPFPVCVEV PSETEAVQGN PMKLRCISCM KREEVEATTV VEWFYRPEGG KDFLIYEYRN GHQEVESPFQ GRLQWNGSKD LQDVSITVLN VTLNDSGLYT CNVSREFEFE AHRPFVKTTR LIPLRVTEEA GEDFTSVVSE HHHHHH