Recombinant humaan Serpin B5/maspin-eiwit

Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, also known as Maspin, is a tumor suppressor protein of serine proteinase inhibitor family. It plays an essential role in embryonic development through critical roles in cell adhesion. Also, it is present in normal breast and prostatic epithelial cells but downregulated in the respective carcinomas. Recombinant human Maspin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, Serpin B5, Protease inhibitor 5, SERPINB5, PI5, Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor, clade B, member 5, Ovalbumin, PI-5, Serpin peptidase inhibitor, Serpin peptidase inhibitor, clade B (ovalbumin), member 5, SERPINB5, Spi5, Spi7.

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

< 1 EU per 1ug of protein (determined by LAL method)

> 95% by SDS-PAGE

44.2 kDa (395aa) confirmed by MALDI-TOF

Serpin B5, Maspin, Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5, Serpin B5, Protease inhibitor 5, SERPINB5, PI5, Serine (or cysteine) proteinase inhibitor clade B (ovalbumin) member 5 Serine (or cysteine) peptidase inhibitor, clade B, member 5, Ovalbumin, PI-5, Serpin peptidase inhibitor, Serpin peptidase inhibitor, clade B (ovalbumin), member 5, SERPINB5, Spi5, Spi7., ATGP0331-10 µg, ATGP0331-20 µg, ATGP0331-50 µg, ATGP0331-100 µg, ATGP0331-250 µg, ATGP0331-500 µg, ATGP0331-1 mg, ATGP0331-10, ATGP0331-20, ATGP0331-50, ATGP0331-100, ATGP0331-250, ATGP0331-500, ATGP0331-1

Lockett J., et al. (2006) . J Cell Biochem. 97 (4) :651-60.; ; Khalkhali Ellis Z., et al. (2006) . Clin Cancer Res. 12 (24) :7279-83.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol

Tags & Cell Markers

AY893387

P36952

Human

MGSSHHHHHH SSGLVPRGSH MDALQLANSA FAVDLFKQLC EKEPLGNVLF SPICLSTSLS LAQVGAKGDT ANEIGQVLHF ENVKDVPFGF QTVTSDVNKL SSFYSLKLIK RLYVDKSLNL STEFISSTKR PYAKELETVD FKDKLEETKG QINNSIKDLT DGHFENILAD NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRVNKT DTKPVQMMNM EATFCMGNID SINCKIMELP FQNKHLSMFI LLPKDVEDES TGLEKIEKQL NSESLSQWTN PSTMANAKVK LSIPKFKVEK MIDPKACLEN LGLKHIFSED TSDFSGMSET KGVALSNVIH KVCLEITEDG GDSIEVPGAR ILQHKDELNA DHPFIYIIRH NKTRNIIFFG KFCSP