Recombinant humaan Serpin D1/heparine cofactor II-eiwit

SERIND1 is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. This protein contains five exons and four introns. It shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency. Recombinant human SERIND1 protein, fused to His-tag at N-terminus, was expressed in E. coli

Heparin cofactor 2 precursor, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 85% by SDS-PAGE

53.3 kDa (465aa)

Serpin D1, Heparin cofactor II, Heparin cofactor 2 precursor, D22S673, HC2, HCF2, HCII, HLS2, LS2, THPH10, ATGP2765-10 µg, ATGP2765-20 µg, ATGP2765-50 µg, ATGP2765-100 µg, ATGP2765-250 µg, ATGP2765-500 µg, ATGP2765-1 mg, ATGP2765-10, ATGP2765-20, ATGP2765-50, ATGP2765-100, ATGP2765-250, ATGP2765-500, ATGP2765-1

Van Deerlin V.M.D., Tollefsen D.M. (1991) J. Biol. Chem. 266:20223-20231.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea

Cardiovascular

NP_000176

P05546

Human

DFHKENT VTNDWIPEGE EDDDYLDLEK IFSEDDDYID IVDSLSVSPT DSDVSAGNIL QLFHGKSRIQ RLNILNAKFA FNLYRVLKDQ VNTFDNIFIA PVGISTAMGM ISLGLKGETH EQVHSILHFK DFVNASSKYE ITTIHNLFRK LTHRLFRRNF GYTLRSVNDL YIQKQFPILL DFKTKVREYY FAEAQIADFS DPAFISKTNN HIMKLTKGLI KDALENIDPA TQMMILNCIY FKGSWVNKFP VEMTHNHNFR LNEREVVKVS MMQTKGNFLA ANDQELDCDI LQLEYVGGIS MLIVVPHKMS GMKTLEAQLT PRVVERWQKS MTNRTREVLL PKFKLEKNYN LVESLKLMGI RMLFDKNGNM AGISDQRIAI DLFKHQGTIT VNEEGTQATT VTTVGFMPLS TQVRFTVDRP FLFLIYEHRT SCLLFMGRVA NPSRS