Recombinant humaan serumamyloïde A1/SAA1-eiwit

Serum amyloid A1 (SAA1) protein is made primarily in the liver and circulates in low levels in the blood. This protein appears to play a role in the immune system. Levels of this protein increase in the blood and other tissues under conditions of inflammation. SAA1 may help repair damaged tissues, acts as an antibacterial agent, and signal the migration of germ-fighting cells to sites of infection. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid arthritis. Recombinant Serum amyloid A protein was expressed in E. coli and purified by using conventional chromatography techniques.

SAA1, serum amyloid A1, PIG4, TP53I4, SAA, Tumor protein p53 inducible protein 4, Amyloid fibril protein AA

E.coli

Human

His-Tag

SDS-PAGE

1 mg/mL (determined by Bradford assay)

> 95% by SDS-PAGE

13.9 kDa (125aa) confirmed by MALDI-TOF

Serum Amyloid A1, SAA1, ATGP0373-10 µg, ATGP0373-20 µg, ATGP0373-50 µg, ATGP0373-100 µg, ATGP0373-250 µg, ATGP0373-500 µg, ATGP0373-1 mg, ATGP0373-10, ATGP0373-20, ATGP0373-50, ATGP0373-100, ATGP0373-250, ATGP0373-500, ATGP0373-1

Betts JC., et al. (1991) Scand J Immunol. 34 (4) :471-82. ; ; Yilmaz E., et al. (2003) Turk J Pediatr. 45 (3) :198-202.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing, 10% glycerol

Immunology

AAI05797

P0DJI8

Human

MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS DARENIQRFF GHGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY