Recombinant humaan serumamyloïde A4/SAA4-eiwit

SAA4 is a constitutively expressed protein belonging to the SAA family. It is a major acute phase reactant and an apolipoprotein of the HDL complex. SAA4 is constitutively expressed only in humans and mice, is associated almost entirely with lipoproteins of the high density range. Its physiological function is unknown and its serum concentration has no relationship with those of other major apolipoproteins. The presence of SAA4 mRNA and protein in macrophage derived foam cells of coronary and carotid arteries suggested a specific role of human SAA4 during inflammation including atherosclerosis. Recombinant human SAA4 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Serum amyloid A-4 protein, CSAA, Constitutively expressed serum amyloid A protein

E.coli

Human

His-Tag

SDS-PAGE

0.5 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

14.9 kDa (131aa) confirmed by MALDI-TOF

Serum amyloid A-4 protein, C-SAA, CSAA, Constitutively expressed serum amyloid A protein, ATGP0793-10 µg, ATGP0793-20 µg, ATGP0793-50 µg, ATGP0793-100 µg, ATGP0793-250 µg, ATGP0793-500 µg, ATGP0793-1 mg, ATGP0793-010, ATGP0793-020, ATGP0793-050, ATGP0793-100, ATGP0793-250, ATGP0793-500, ATGP0793-01M

Badolato R., et al. (2000) J Leukoc Biol. 67 (3) :381-6. ; ; Artl A., et al. (2000) Arterioscler Thromb Vasc Biol. 20 (3) :763-72.;

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 5mM DTT, 0.2M NaCl, 0.5mM EDTA

Immunology

NP_006503.2

P35542

Human

WRSFFKEAL QGVGDMGRAY WDIMISNHQN SNRYLYARGN YDAAQRGPGG VWAAKLISRS RVYLQGLIDY YLFGNSSTVL EDSKSNEKAE EWGRSGKDPD RFRPDGLPKK Y