Recombinant humaan sFRP-3/FRZB-eiwit

FRZB is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. Recombinant human FRZB protein, fused to His-tag at N-terminus, was expressed in E. coli.

SRFP3, SFRP3, Secreted frizzled-related protein 3, OS1, hFIZ, FZRB, FRZB-PEN, FRZB1, FRZB, FRP-3, FRITZ, FRE

E.coli

Human

His-Tag

SDS-PAGE, Denatured

1 mg/mL (determined by Bradford assay)

> 90% by SDS-PAGE

35 kDa (316aa)

FRE, FRITZ, FRP 3, FRP3, FRP-3, FRZB, FRZB 1, FRZB1, FRZB-1, FRZB-PEN, FZRB, hFIZ, OS1, Secreted frizzled related protein 3, Secreted frizzled-related protein 3, SFRP 3, SFRP3, SFRP-3, SRFP 3, SRFP3, SRFP-3, ATGP1888-10 µg, ATGP1888-20 µg, ATGP1888-50 µg, ATGP1888-100 µg, ATGP1888-250 µg, ATGP1888-500 µg, ATGP1888-1 mg, ATGP1888-010, ATGP1888-020, ATGP1888-050, ATGP1888-100, ATGP1888-250, ATGP1888-500, ATGP1888-01M

Baker-Lepain JC, Lynch JA, et al. (2012) . Arthritis Rheum. 64 (5) :1457-65. ; ; Ekstrom EJ, Sherwood V, et al. (2011) . PLoS One. 6 (4) :e18674.

Can be stored at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Liquid in. 20 mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Stem cell

NP_001454

Q92765

Human

AACEPVR IPLCKSLPWN MTKMPNHLHH STQANAILAI EQFEGLLGTH CSPDLLFFLC AMYAPICTID FQHEPIKPCK SVCERARQGC EPILIKYRHS WPENLACEEL PVYDRGVCIS PEAIVTADGA DFPMDSSNGN CRGASSERCK CKPIRATQKT YFRNNYNYVI RAKVKEIKTK CHDVTAVVEV KEILKSSLVN IPRDTVNLYT SSGCLCPPLN VNEEYIIMGY EDEERSRLLL VEGSIAEKWK DRLGKKVKRW DMKLRHLGLS KSDSSNSDST QSQKSGRNSN PRQARN